Modulation of the allosteric and vasoregulatory arms of erythrocytic oxygen transport.

One possible exception to the general lack of benefit of more aggressive RBC transfusion is the patient with acute myocardial infarction, with the recently reported MINT trial showing a strong trend in outcomes ( Carson et al., 2023 ) interpreted by some ( Bloch and Tobian, 2023 ) as supporting a more liberal transfusion strategy in these patients and, by extension, a recognition that one size does not fit all in RBC transfusion decision-making.

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