A stepwise multiple regression analysis showed that HbA1c ( P < 0.001) and Cystatin C ( P = 0.03) were associated to the duration of diabetes at sampling while MMP-9, lipocalin-2, and FGF21 did not reach statistical significance.
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Cystatin C as an adjunct to HbA1c may prove useful in predicting the development of diabetic complications in children and adolescents with type 1 diabetes.
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