Airway "Resistotypes" and Clinical Outcomes in Bronchiectasis.

Assessment of bronchiectasis resistomes at the level of individual genes demonstrated a highly significant effect for geographic patient origin ( P = 0.006), one that remained even after accounting for etiology ( Figure 3B ).

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In contrast, etiological association with resistance gene profiles failed to reach statistical significance in PERMANOVA analysis of matched patients, suggesting that resistomes relate most strongly to a patient’s country of origin rather than underlying etiology ( Figure 3C ).

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