As observed in the direct competition assay, Alpha S showed significantly increased viral spread compared to Wuhan-Hu-1 (1.66 ± 0.24 fold; p = 0.0009 by two-tailed t -test), the spread of Delta S was improved but did not reach statistical significance (1.59 ± 0.39 fold; p = 0.07 by two-tailed t -test), and Mu S showed significantly decreased spread (0.82 ± 0.58 fold; p = 0.008 by two-tailed t -test; Fig. 4 B).
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An efficient plasmid-based system for the recovery of recombinant vesicular stomatitis virus encoding foreign glycoproteins.
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