Lack of correlation between <i>in vitro</i> and within patient measures of <i>P. aeruginosa</i> biofilms in cystic fibrosis.

However, when PA was grown in the chamber wells in LB with 5 % sputum supernatant, the in vitro model showed a trend toward statistical significance with the ex vivo biovolume measures (p = 0.051; r = 0.6) ( Fig. 1 A).

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We observed that PA biovolume, aggregation and Psl antibody binding (normalized per PA biovolume) in CF sputum did not correlate with the in vitro model, although a trend towards significance in the biovolume relationship was observed with the addition of sputum supernatant to the in vitro model. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2024 Feb 17; Revised 2024 May 7; Accepted 2024 Jun 4; Collection date 2024 Jun 15.

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