Identification of Gut Microbiome Signatures Associated with Indole Pathway in Tryptophan Metabolism in Patients Undergoing Hemodialysis.

The computation of alpha diversity indices, which quantifies the microbial richness and evenness within each patient group, showed that high and low concentrations of tryptophan revealed a significant difference in Shannon diversity ( p = 0.031), hinting at a distinct community composition between these groups, although the Simpson ( p = 0.090) and inverse Simpson ( p = 0.211) indices did not reach statistical significance ( Figure 1 A).

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