Evaluating the immunologically "cold" tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4 + and CD8 + T cells in breast cancer mouse models.

Breast Cancer Res · 2024 · PMC11201779 · PMID 38918836

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

Intratumoral [ 89 Zr]Zr-DFO-CD4 SUV peak showed trending increases in the responder tumors in the MMTV-HER2 model on day 6, but these did not reach statistical significance (Supplemental Fig. 3 B, p = 0.09).

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a decreasing trendno p-value reported

2 C, p = 0.0619) showed a decreasing trend in the responder group compared to the non-responder group.

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