Low Cell Bioenergetic Metabolism Characterizes Chronic Lymphocytic Leukemia Patients with Unfavorable Genetic Factors and with a Better Response to BTK Inhibition.

Similar to the overall population, a higher WBC count was observed in the CLL low group compared to the CLL high (median CLL low: 47,200—range 20,900–159,000; median CLL high: 17,955—range 3880–30,000), although in this subpopulation, the differences did not reach statistical significance ( p = 0.07) due to the small sample size ( Table 3 ).

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