While current guidelines recommend hormonal therapies such as combined oral contraceptives, gestagens, or GnRH agonists and antagonists [ 16 ], researchers constantly search for hormone-free alternatives, driven by a clear trend away from hormones in this particular patient collective, as well as lacking therapeutic options for women trying to conceive, yet suffering from severe endometriosis-associated symptoms, women for whom hormonal therapies are not adequate due to their contraceptive effect.
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Recent Advances in Endometriosis Pathophysiology and Pharmacological Treatment.
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