Kinetics of cardiovascular and inflammatory biomarkers in paediatric dengue shock syndrome.

Utility of enrolment biomarkers in predicting recurrent shock and respiratory distress At ICU admission with shock, patients with higher Syndecan-1 levels were more likely to develop recurrent shock (OR = 1.82, 95% CI 1.07–3.35, P = 0.038); however, after adjustment for multiple comparisons, the association did not reach statistical significance (at our predefined level of P < 0.01).

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In contrast, the natriuretic peptides, including ANP and NT-proBNP, followed an increasing trend during ICU admission and continued to be raised at the follow-up visit.

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