Individualized high-resolution analysis to categorize diverse learning and memory deficits in tau rTg4510 mice exposed to low-intensity blast.

With the HEMI groups, although LIB appeared to induce a slight decrease in reversal learning during both dark phases, these differences did not reach statistical significance upon comparing between the HEMI Sham and Blast groups [Time: F (4.687, 103.2) = 39.35, p < 0.0001; Group: F (1, 30) = 0.2318, p = 0.6337; Time × Group: F (46, 1,380) = 0.4483, p = 0.9995; Subject: F (30,1,380) = 26.52, p < 0.0001]. 3.2 Cognitive flexibility of the reversal learning The main purpose of the reversal learning phase is to evaluate cognitive learning flexibility of the HEMI and NCAR mice.

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