Clinicopathological Factors as Predictors for Establishment of Patient Derived Head and Neck Squamous Cell Carcinoma Organoids.

Head Neck Pathol · 2024 · PMC11213837 · PMID 38940869

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

There was a strong trend towards an improved success rate of PDOs from resection samples as compared to biopsies: 136/196 (69.4%) vs. 5/12 (41.7%), p = 0.06 (Table 3 ).

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a positive trendno p-value reported

In conclusion, this study found a positive trend between age and successful organoid outgrowth in patients with HNSCC younger than 68 years and emphasizes the value of efficient tumor sampling to achieve successful PDO establishment.

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