FSHD samples show a significant trend of having a lower number of nuclei per myotube compared with the control (FSHD: 15.47 ± 0.60; DEL5: 24.60 ± 1.29; control: 27.42 ± 1.07; mean ± SE; control vs.
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Single-cell spatial transcriptomics reveals a dystrophic trajectory following a developmental bifurcation of myoblast cell fates in facioscapulohumeral muscular dystrophy.
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