The MTT test performed on non-differentiated cells showed only marginally significant toxic effect of diazoxide (Fig. 5 b), while no effect on MTT metabolic turnover was observed after 24 hours of glibenclamide presence in growth medium.
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The impact of ATP-sensitive potassium channel modulation on mitochondria in a Parkinson's disease model using SH-SY5Y cells depends on their differentiation state.
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