A skin-specific α-Synuclein seeding amplification assay for diagnosing Parkinson's disease.

NPJ Parkinsons Dis · 2024 · PMC11222486 · PMID 38961119

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did not reach statistical significanceno p-value reported

Interestingly, the maximum ThT fluorescence (Fmax) was higher in the Nunc (97.00 ± 2.64%) compared to the polystyrene group (93.01 ± 2.31%) after 12 h of amplification using the modified SAA, although this difference did not reach statistical significance (Fig. 4f ).

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highly significantno p-value reported

Our data unequivocally show that selecting the appropriate conditions for seed amplification is highly significant.

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