Factors associated with cognitive function in patient with Alzheimer's disease with newly prescribed acetylcholinesterase inhibitors: A 1-year retrospective cohort study.

Combined use of BZRA also showed a trend toward significance ([AOR]: 1.290, 95% CIs: 0.996 to 1.672). 4.

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The main findings were as follows: (1) patients with a lower baseline BMI exhibited a higher risk of cognitive decline after 1 year of AChEI treatment compared to those with a higher baseline BMI; (2) the concurrent use of antipsychotics in patients was associated with an increased risk of disease progression; and (3) concurrent usage of BZRA in patients with AD showed a significant trend with cognitive worsening.

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