In 15 μM CTZ-treated MM.1S cells, the level of p65 was significantly decreased (p-value < 0.05), whereas in 15 μM CTZ-treated NCI-H929 cells, a reduction in p65 levels was noted, although it did not reach statistical significance.
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Clotrimazole inhibits growth of multiple myeloma cells in vitro via G0/G1 arrest and mitochondrial apoptosis.
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