Upon induction of dyskinesia by high-dose levodopa ( Figures S3 D and S3E), the ΔF/F signals in FosTRAP2-PF-GCaMP mice displayed a slight increase, but did not reach statistical significance when compared to the baseline or to those in FosTRAP2-PF-EGFP mice ( Figures 2 I–2K).
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Bidirectional regulation of levodopa-induced dyskinesia by a specific neural ensemble in globus pallidus external segment.
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