fbl-1(k206) alleles showed significantly longer defecation cycles compared to the wild type after day 5 and fbl-1(k201) showed a trend toward suppression of the mig-17 defecation decline at day 5, although it was not statistically significant (t-test: p = 0.069) ( Fig 3D–3F ).
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Mutations in fibulin-1 and collagen IV suppress the short healthspan of mig-17/ADAMTS mutants in Caenorhabditis elegans.
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