Patterns of neuromyelitis optica spectrum disorder attacks in different age groups and sexes depending on the status of immunosuppressive therapy: A retrospective cohort study.

Additionally, we noticed that in men, although the risk of relapse in patients in older age groups was lower compared with the youngest age group, patients aged > 50 years showed a trend towards elevated risk of relapse compared with patients aged 40–49 years (hazard ratio [HR] 0.80 vs. 0.52), indicating a potential nonlinear association between onset age and recurrent relapses.

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