The imbalance of pulmonary Th17/Treg cells in BALB/c suckling mice infected with respiratory syncytial virus-mediated intestinal immune damage and gut microbiota changes.

Microbiol Spectr · 2024 · PMC11237571 · PMID 38727214

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The excessive release of IL-22 in lung tissue may stimulate the expression of RegIIIγ in intestinal tissue via the circulation Compared with the normal group, the expression of IFN-γ in the lungs and intestines of the RSV-infected group showed a trend of first increasing and then decreasing, reaching a maximum value one the third day after infection, with a significant difference ( P < 0.01, Fig. 4A ).

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