Plasmodium falciparum gametocyte production correlates with genetic markers of parasite replication but is not influenced by experimental exposure to mosquito biting.

Although it did not reach statistical significance, transcript levels of sir2a on timepoint T were negatively associated with ring-stage density on timepoint T +14 (fold change = 0.78, 95% CI = 0.47–1.30, P = 0.341, t-test, Table 1 ).

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