Identification of miRNAs and Their Target Genes Associated with Sunitinib Resistance in Clear Cell Renal Cell Carcinoma Patients.

We observed that high levels of miR-223 (although it did not reach statistical significance) and low levels of PRDM1 , SAV1 and FLT1 were indeed associated with shorter OS of 49, 28, 15 and 54 months, respectively, compared to medians of 134, 110, 110 and 183 months, respectively, for patients with low expression of miR-223 and high expression of` PRDM1 , SAV1 and FLT1 ( Figure 7 ).

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