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Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review.

J Headache Pain · 2024 · PMC11241973 · PMID 38997662

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The use of GLP-1R agonists was associated with fewer intra-articular injections of steroids and a lower cartilage loss velocity from the medial femoral joint, but the direct effects of GLP-1R agonist, apart from the weight loss-mediated pathway, did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.