Dissimilar Changes in Serum Cortisol after Epileptic and Psychogenic Non-Epileptic Seizures: A Promising Biomarker in the Differential Diagnosis of Paroxysmal Events?

A highly significant correlation, r = 0.55 (Spearman’s correlation, 95% confidence interval is 0.17–0.79, p = 0.006), was found, most probably indicative of a common pathogenetic HPA axis-related mechanism responsible for increasing the level of both hormones during ESs ( Figure 5 A).

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Patients reporting sexual trauma showed a trend toward higher cortisol levels as compared to patients without a reported sexual trauma.

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