EGFR mutations induce the suppression of CD8<sup>+</sup> T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer.

J Transl Med · 2024 · PMC11246587 · PMID 39004699

Europe PMC DOI

hedged sentence

0.1087

closest p · 2.2× alpha

0.1087

boldest claim

The sentences

did not reach statistical significanceP = 0.1087not close (p > 0.1)

The H-scores of TGF-β2 in EGFR 20ins -mutated tumors showed the same trend, but it did not reach statistical significance ( P = 0.1087) (Fig. 1 E).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

EGFR mutations induce the suppression of CD8&lt;sup&gt;+&lt;/sup&gt; T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer.

The sentences

EGFR mutations induce the suppression of CD8<sup>+</sup> T cell and anti-PD-1 resistance via ERK1/2-p90RSK-TGF-β axis in non-small cell lung cancer.