A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model.

Alzheimers Dement · 2024 · PMC11247716 · PMID 38779814

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nominally significantno p-value reported

Setting a relaxed significance threshold ( P value < 0.05), we compared the fold change of DE for the APP effect ( y axis) and BD10‐2 effect ( x axis) to gauge the correlation of genes nominally significant in both (379 genes; Figure 7B ).

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