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Efficacy and safety of different polymyxin-containing regimens for the treatment of pneumonia caused by multidrug-resistant gram-negative bacteria: a systematic review and network meta-analysis.

Crit Care · 2024 · PMC11247855 · PMID 39004760

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Our network meta-analysis found that compared to IV polymyxins, IH polymyxins reduced mortality among pneumonia patients with MDR-GNB infections, although this reduction did not reach statistical significance.

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