Combined DNA Methylation and Gastric Microbiome Marker Predicts <i>Helicobacter pylori</i>-Negative Gastric Cancer.

Gut Liver · 2024 · PMC11249944 · PMID 38509701

Europe PMC DOI

hedged sentences

0.0620

closest p · 1.2× alpha

0.0670

boldest claim

The sentences

marginal significancep=0.062so close (0.05 < p ≤ 0.1)

The model including age, sex, atrophy, metaplasia, TWIST1 , and GCMI showed an AUC of 0.994 (95% CI, 0.976 to 1.000), which was higher than that of the model using age and sex (AUC, 0.780; 95% CI, 0.556 to 1.000) with marginal significance (p=0.062).

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did not reach statistical significancep=0.067so close (0.05 < p ≤ 0.1)

However, the association did not reach statistical significance after further adjusting for age and atrophy (OR, 9.04; 95% CI, 0.86 to 95.17; p=0.067) ( Supplementary Table 4 ).

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