Pharmacokinetics of Generic Pediatric Dolutegravir Dispersible Tablet in Thai Young Children Living With HIV Weighing Below Twenty Kilograms.

6 At the time this study was initiated in 2021, the ODYSSEY pharmacokinetic substudy of 11 children weighing 6 to <10 kg using 15 mg of DTG-DT showed a trend of lower DTG C 24 with high intersubject variability compared with older children using WHO WB dosing and adults using DTG-FCT 50 mg. 11 In August 2023, IMPAACT 2019 published pharmacokinetic data on DTG in children using abacavir (ABC)/lamivudine (3TC)/DTG fixed-dose combination DT, which confirmed WHO WB dosing of DTG-DT in children 6 to <25 kg.

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