Barely Significant
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Trends in peripheral artery disease and critical limb ischemia hospitalizations among cocaine and methamphetamine users in the United States: a nationwide study.

Front Cardiovasc Med · 2024 · PMC11251891 · PMID 39022622

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a decreasing trendno p-value reported
an increasing trendno p-value reported
Results Between 2008 and 2020, PAD-related hospitalizations showed an increasing trend in Hispanics, African Americans, and western states, while a decreasing trend in southern and Midwestern states ( p -trend <0.05).

also in 47,180 other papers

a strong trendno p-value reported
We also showed a strong trend of PAD among substance users, especially those who use methamphetamine.

also in 5,725 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.