The best linear unbiased prediction (BLUP) method as a tool to estimate the lifetime risk of pancreatic ductal adenocarcinoma in high-risk individuals with no known pathogenic germline variants.

6 b) had slightly higher mean EGV (any cancer BLUP model: 0.131 IQR [-0.365;0.673], PDAC BLUP model: -0.014 IQR [-0.171;0.352]), lower than the mean EGV of individuals with solid lesions and slightly higher than the mean EGV for individuals with cysts and no pancreas lesion, although this did not reach statistical significance.

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