Mutant androgen receptor induces neurite loss and senescence independently of ARE binding in a neuronal model of SBMA.

Furthermore, DHT treatment significantly reduced Tubb3 gene expression (encoding β-III-Tubulin protein) for AR10Q, AR112Q, and AR111Q K387/519R 4 d after Dox and DHT treatment; this did not reach statistical significance for AR111Q V582F ( SI Appendix , Fig.

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