Similar results were also obtained in the spleen; however, the difference did not reach statistical significance most probably due to the existence of variable patterns as compared to diffuse pattern of T cell infiltrates ( SI Appendix , Fig.
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The sentences
The flow cytometry analysis of tumors showed no difference in the percentage of CD4-positive cells in control and IcosL-expressing tumors, but there was a highly significant increase in the percentage of CD8-positive T cells in IcosL-expressing tumors ( SI Appendix , Fig.