Barely Significant
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Epigenetic disease markers in primary sclerosing cholangitis and primary biliary cholangitis-methylomics of cholestatic liver disease.

Hepatol Commun · 2024 · PMC11262819 · PMID 39023332

Europe PMCDOI
3
hedged sentences
0.0673
closest p · 1.3× alpha
0.0673
boldest claim

The sentences

fell short of significancep = 0.0673so close (0.05 < p ≤ 0.1)
In addition, patients with PSC with small duct disease had lower AgeAccelGrim values than those without, but again, this difference fell short of significance ( p = 0.0673).

also in 60 other papers

did not reach statistical significanceno p-value reported
However, the elevation of AgeAccelGrim in patients with cirrhosis compared to those without cirrhosis did not reach statistical significance in PBC (Figure 1 F).

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highly significantno p-value reported
One compelling finding was tumor necrosis factor receptor superfamily member 1B, which was among the top 3 increased proteins in patients with cirrhosis compared to patients with noncirrhotic PSC and PBC and highly significant in the PSC and PBC case-control analyses. tumor necrosis factor receptor superfamily member 1B encodes TNFR2, one of the 2 TNFα receptors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.