Deregulation of MicroRNA-146a and 155 expression levels might underlie complicated pregnancy in Toxoplasma Gondii seronegative women.

Statistical analyses defined a high plasma level of MiR-155 as the highly significant predictor for oncoming pregnancy complications and high levels of both microRNAs as predictors for the presence of toxoplasmosis despite seronegativity.

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In support of this assumption, the correlation between seropositivity and adverse pregnancy outcome was weakly significant and ROC curve analysis defined seropositivity as a weak significant predictor, while regression analysis excluded serology as a predictor for pregnancy outcomes.

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