Barely Significant
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Adverse Events of PD-1, PD-L1, CTLA-4, and LAG-3 Immune Checkpoint Inhibitors: An Analysis of the FDA Adverse Events Database.

Antibodies (Basel) · 2024 · PMC11270294 · PMID 39051335

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a strong trendno p-value reported
For instance, CTLA-4 inhibitors were associated with a higher incidence of colitis and diarrhea, while PD-1 inhibitors showed a strong trend toward immune-related AEs, again, congruent with the current literature [ 29 , 30 ].

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