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Prolonged Sleep Deprivation Induces a Reprogramming of Circadian Rhythmicity with the Hepatic Metabolic Transcriptomic Profile.

Biology (Basel) · 2024 · PMC11274269 · PMID 39056724

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a decreasing trendno p-value reported
However, the TC and TG levels in SD mice showed a decreasing trend, corresponding to variations in feeding times ( Figure 2 G–I).

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In the SD group, alanine aminotransferase (ALT) levels exhibited an upward trend but did not reach statistical significance ( Figure 2 I,J), whereas aspartate aminotransferase (AST) levels significantly increased overall and at multiple time points ( Figure 2 K,L), suggesting potential liver or organ damage.

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