The Evolution of Genetic Variability at the <i>LRRK2</i> Locus.

Genes (Basel) · 2024 · PMC11275506 · PMID 39062657

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0003

boldest claim

The sentences

highly significantp = 4.50 × 10 −18actually significant

The distribution of iHS scores for the entirety of the chromosome 12 iHS values (minus the LRRK2 locus) was bootstrapped and suggested that this cluster was highly significant compared to scores for the rest of the chromosome ( p = 4.50 × 10 −18 ).

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nominally significantp = 2.95 × 10 −4actually significant

Curiously, iHS scores within the LRRK2 locus from 40.2 to 41.0 Mb were nominally significant for rs34637584_G wild-type alleles (GG all = 422, p = 2.95 × 10 −4 to 1.61 × 10 −6 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.