At 1 h after consumption of a single dose of 600 mg, the difference in the number of circulating monocytes ( Figure 2 A) was lower than at 1 h after consuming the placebo, reaching a statistical trend ( p < 0.1), suggesting an increased trafficking of monocytes into tissue.
The expression of CD25 on monocytes ( Figure 3 A) showed a gradual increase over the 2 h after consumption, but the difference in CD25 expression after consuming CELMPs compared to the placebo did not reach statistical significance.
Selective reduction in pro-inflammatory cytokines was seen at 1, 2, and 24 h, where the 2-h reduction was highly significant for IL-6, IFN-γ, and IL-13.