The Autophagic and Apoptotic Death of Forebrain Neurons of Rats with Global Brain Ischemia Is Diminished by the Intranasal Administration of Insulin: Possible Mechanism of Its Action.

Intranasal administration of insulin to rats enlarged the number of live neurons in the frontal cortex that survived ischemia and reperfusion from 48.76 ± 2.33 to 59.38 ± 1.16/standard area; the difference is quite significant ( p < 0.01).

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