Short- and Long-Term Outcomes in Elderly Patients with Resectable Esophageal Cancer: Upfront Esophagectomy Compared to Surgery after Neoadjuvant Treatments.

The toxicity of chemotherapy and/or radiotherapy regimens may be significant in geriatric patients and limited physiological reserve could undermine the chance to complete multimodal oncological treatments.

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When looking at tumor histology, the survival analysis for EAC showed a tendency towards better OS for the NAT group, but the difference did not reach statistical significance ( Figure 3 a).

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