IL4/IL13 cytokines (50 ng/ml, 24 h) induced TP63 but showed a trend towards inhibition of TSC22D3/GILZ , a classic GR-target gene with anti-inflammatory roles in most cell types (Fig. 3a, b ).
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Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes.
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