TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment.

J Immunother Cancer · 2024 · PMC11284822 · PMID 39060022

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showed a trendno p-value reported

Moreover, the ratio of M1 macrophages over M2 also showed a trend for an increase at the same time point in both models ( figure 4D ).

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