CoREST MI08173 ; tim -Gal4/+; UAS- LSD1 RNAi/+ (percentage rhythmicity of 48.4% compared with 54.8% in CoREST MI08173 ; tim- Gal4/+) showed a trend towards an enhanced phenotype of CoREST MI08173 in the percentage of rhythmicity and power value ( figure 4 d , f ).
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The CoREST complex regulates multiple histone modifications temporal-specifically in clock neurons.
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