13 Notably, the number of children and adolescents with IBD is continuously rising, as, for example, monitored in Canada, 14 and a clear trend in rising incidence and prevalence has been documented across the globe. 15 A similar development has been documented for metabolic diseases in children and adolescents, for example, 3% of children and 5% of adolescents worldwide exhibited the MS in 2020. 16 Likewise, the prevalence of the MS in ad
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