The spectrum of cardiac abnormalities in patients with acromegaly: results from a case-control cardiac magnetic resonance study.

Similarly, our data showed that, in the overall acromegaly cohort, hormonal levels at diagnosis were not associated with worse cardiac outcomes at the time of CMR analysis; nevertheless, we observed a trend towards higher IGF1xULN levels at diagnosis in patients with active disease compared to the ones in remission at the time of study enrolment: although this difference did not reach statistical significance, likely due to the small sample size, these results would suggest a potential impact of pre-diagnosis disease severity on the development of cardiac abnormalities.

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