Results PheWAS analysis reveals FTO gene associations across psychiatric traits The phenome-wide association study (PheWAS) of the FTO gene considered 4,756 GWAS datasets encompassing a total of 3,302 phenotypic traits and yielded nominally significant associations with 791 traits across 27 domains (Fig.
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Examining the association between the FTO gene and neuroticism reveals indirect effects on subjective well-being and problematic alcohol use.
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