D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells.

Haematologica · 2024 · PMC11290548 · PMID 38235501

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did not reach statistical significanceno p-value reported

Surface expression of MHC class I molecules also decreased during D-2-HG treatment but the decrease did not reach statistical significance ( Online Supplementary Figure S1F ).

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