H292 cells showed a trend to increase the synthesis of nitrogenous bases, such as purine synthesis (guanosine) and pyrimidine (cytidine, uracil, uridine) indicating that they might adapt to conditions of oxidative stress, at least the cells that are surviving (Supplementary Figure S5C).
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Metabolic profiling and combined therapeutic strategies unveil the cytotoxic potential of selenium-chrysin (SeChry) in NSCLC cells.
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